So Damaged Sperm Healthy Because 'Protein'

Jakarta, Various things can make a man become fertile or infertile, even in men who have healthy sperm. One reason is the damage to the protein chaperone (chaperones).

Researchers from Australia said that men with healthy sperm is likely to be infertile if damaged proteins companion. This will prevent damage to the sperm proteins to recognize the egg cell.

Incoming sperm will swim through the reproductive tract, as sperm begin to approach the egg cell then this will escort the chaperone proteins to the surface of sperm cells. At that sperm have the capacity to recognize the egg cell.

"If someone does not have a chaperone protein, although it has receptors in the cell, then he can not recognize the receptors on the cell surface which makes it difficult to recognize the egg," said Professor John Aitken from the University of Newcastle, as quoted from abc.net.au, Wednesday (05/04/2011).

Aitken said that about 1 in 20 men experience infertility (infertile). Most of the cause because it does not produce enough sperm, but there are other causes which make the sperm lost the ability to fertilize an egg.

In this study Aitken using mass spectrometry to analyze the protein structure of sperm from the male fertile and infertile. Obtained HSP2A known chaperone proteins are in low concentrations in men who are infertile. What happened to the male infertility is a protein chaperone that carries the defective receptor complex.

"These results could help develop a male contraceptive that new or infertility treatment, for example by trying to activate the chaperone proteins," said Aitken.

Generally the quality of male sperm will decrease with age and the presence of a decreased risk of genetic disease. Level of male fertility will begin to decrease when the age of 35 years and over, although not such a drastic decline of women.

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