Osteoporosis Drugs Can Make Eye Disease


Jakarta, novice users of osteoporosis medications called oral bisphosphonates may be at high risk of serious eye inflammation disease. Some eye inflammation may result from this drug.

It is based on research to a new study published in the journal CMAJ.

Oral bisphosphonates such as Fosamax and Actonel are the drugs most widely prescribed to prevent or slow osteoporosis, a disease that causes bones to be very weak.

Previous research also has linked these drugs with problems such as broken bones are not uncommon, irregular heartbeat, as well as esophageal cancer and colon cancer.

In addition, several other cases reported an association between these drugs with inflammation of the eye - anterior uveitis and scleritis - which can cause serious vision problems.

Uveitis is inflammation of the eye called the uvea consists of the iris, choroid and siliaris corpus. Klafisikasinya depending on the affected part of the uvea Anterior Uveitis, Intermediate Uveitis, Posterior Uveitis Uveitis and Pan. While scleritis is an inflammation of the whites of the eyes (sclera).

In this new study, researchers from Canada compares 11 000 novice users of oral bisphosphonates and 920 000 nonusers. Novice users have high levels of incidence of 29 per 10,000 people / year for uveitis disease, and 63 per 10.000/tahun to scleritis, compared with respectively 20 per 10,000 and 36 per 10,000 non-users. Per-orang/tahun count is determined by multiplying the number of participants with a number of years of drug consumption.

"We found that novice users of bisphosphonates are at increased risk of developing the disease scleritis and uveitis," said Dr. Mahyar Etminan of Child and Family Research Institute and Department of Medicine at the University of British Columbia as reported from MSN Health on Wednesday (18/04/2012).

"Our study highlights the need for doctors to inform the signs and symptoms of scleritis and uveitis in patients so that appropriate treatment can be sought and its complications can be avoided," he added.

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